Common Blood Tests for Chronic Inflammatory Disease Conditions



In the realm of healthcare, blood tests are a crucial tool for diagnosing and monitoring various diseases. For chronic inflammatory conditions, certain blood tests can provide valuable insights into the patient’s inflammatory status. This blog will discuss some of the common blood tests used in the diagnosis and management of chronic inflammatory diseases.

  1. Erythrocyte Sedimentation Rate (ESR)

The Erythrocyte Sedimentation Rate (ESR) is a simple and cost-effective test that measures the rate at which red blood cells settle at the bottom of a test tube in one hour. An elevated ESR indicates the presence of inflammation in the body. However, it’s worth noting that ESR is a non-specific test and can be elevated in many different conditions.

  1. C-Reactive Protein (CRP)

C-Reactive Protein (CRP) is an acute-phase protein produced by the liver in response to inflammation. It’s one of the most used markers for inflammation. The CRP test measures the level of this specific protein in the blood. An elevated CRP level can indicate an ongoing inflammatory response in the body. For more detailed information on CRP, check out our article [C-Reactive Protein: A Key Player in Chronic Inflammatory Diseases].

  1. Procalcitonin (PCT)

Procalcitonin (PCT) is another protein that increases during inflammation, particularly in response to bacterial infections. It’s an extremely sensitive marker for conditions like pneumonia and sepsis, and it can also indicate how these conditions are progressing or responding to treatment.

  1. Plasma Viscosity (PV)

Plasma Viscosity (PV) is a measure of the thickness of the blood. Inflammatory conditions can increase plasma viscosity as they often lead to an increase in fibrinogen, a protein that makes the blood thicker.

  1. Full Blood Count

A full blood count is a broad screening test to check for such disorders as anaemia, infection, and many other diseases. It is a group of tests that examine different parts of the blood and includes White Blood Cells (WBCs), Red Blood Cells (RBCs), and platelets.

  1. Fasting Insulin and HbA1C

Fasting insulin and HbA1C are important tests for inflammation related to metabolic disorders like diabetes. Fasting insulin measures your baseline insulin levels, while HbA1C provides an average of your blood sugar levels over the past 3 months.

  1. Serum Ferritin

Serum ferritin is a measure of stored iron in your body and can be elevated in chronic inflammatory conditions.

These tests provide valuable information about a patient’s inflammatory status. However, it’s important to remember that these tests are not disease specific. They can be influenced by various factors and should be interpreted in conjunction with clinical findings and other diagnostic procedures.

As healthcare professionals, understanding these tests allows us to make more accurate diagnoses, monitor disease progression, and assess treatment efficacy. This knowledge enhances our ability to provide optimal care for our patients with chronic inflammatory diseases.

Furthermore, it’s important to note that while these tests are useful tools, they are not definitive. They should be used as part of a comprehensive approach to patient care that includes a thorough history taking, physical examination, and consideration of other diagnostic tests as appropriate.

In addition to these common tests, there are also more specific tests that may be used depending on the suspected underlying condition. These include autoantibody tests for autoimmune diseases, genetic testing for hereditary conditions, and imaging studies for structural abnormalities.

Finally, it’s crucial to remember that patient care does not end with diagnosis. Regular monitoring using these blood tests can help track disease progression and response to treatment, allowing adjustments to be made as necessary. This proactive approach can help improve patient outcomes and quality of life.

In conclusion, blood tests play a vital role in managing chronic inflammatory diseases. As we continue to advance our understanding and technology, we can expect even more precise and useful tools in our fight against these challenging conditions.


  1. Mayo Clinic. (n.d.). Erythrocyte sedimentation rate.
  2. Harvard Health Publishing. (2020). C-reactive protein test.
  3. MedlinePlus. (2020). Procalcitonin.
  4. Lab Tests Online UK. (2019). Plasma viscosity.
  5. Mayo Clinic. (2020). Complete blood count (CBC).
  6. American Diabetes Association. (2020). The A1C Test & Diabetes.
  7. Lab Tests Online UK. (2018). Ferritin.
  8. NHS Inform. (2020). Blood tests.
  9. National Heart, Lung, and Blood Institute. (2020). Hemoglobin A1C.
  10. Mayo Clinic. (2020). Sed rate (erythrocyte sedimentation rate).
  11. Lab Tests Online UK. (2018). C-Reactive Protein.
  12. MedlinePlus. (2020). Procalcitonin test.
  13. Lab Tests Online UK. (2019). Plasma Viscosity Test.
  14. Mayo Clinic. (2020). Complete blood count (CBC).
  15. American Diabetes Association. (2020). Insulin, Medicines, & Other Diabetes Treatments.
  16. Lab Tests Online UK. (2018). Ferritin Test.


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